Skin or oral mucosa
ELISA, RIA, IHC not established
Human, mouse, rat, other species not tested
(lyophilisate) 1-10 µg/ml Western Blot, 0.5-1 µg/ml ELISA, IHC 2-10 µg/ml (not tested)
Mixture of synthetic peptides (14 AA near N-terminus of the mature HBD-2, 14 AA near N-terminus of the mature rat ß-Defensin-2, and 17 AA near N-terminus of the mature mouse ß-Defensin-2) coupled to KLH for immunisation of rabbits
human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.